학술논문
Swine and poultry pathogens: the complete genome sequences of two strains of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviae
Document Type
Author Abstract
Author
Vasconcelos, Ana Tereza R.; Ferreira, Henrique B.; Bizarro, Cristiano V.; Bonatto, Sandro L.; Carvalho, Marcos O.; Pinto, Paulo M.; Almeida, Darcy F.; Almeida, Luiz G.P.; Almeida, Rosana; Alves-Filho, Leonardo; Assuncao, Enedina N.; Azevedo, Vasco A.C.; Bogo, Mauricio R.; Brigido, Marcelo M.; Brocchi, Marcelo; Burity, Helio A.; Camargo, Anamaria A.; Camargo, Sandro S.; Carepo, Marta S.; Carraro, Dirce M.; de Mattos Cascardo, Julio C.; Castro, Luiza A.; Cavalcanti, Gisele; Chemale, Gustavo; Collevatti, Rosane G.; Cunha, Cristina W.; Dallagiovanna, Bruno; Dambros, Bibiana P.; Dellagostin, Odir A.; Falcao, Clarissa; Fantinatti-Garboggini, Fabiana; Felipe, Maria S.S.; Fiorentin, Laurimar; Franco, Gloria R.; Freitas, Nara S.A.; Frias, Diego; Grangeiro, Thalles B.; Grisard, Edmundo C.; Guimaraes, Claudia T.; Hungria, Mariangela; Jardim, Silvia N.; Krieger, Marco A.; Laurino, Jomar P.; Lima, Lucymara F.A.; Lopes, Maryellen I.; Loreto, Elgion L.S.; Madeira, Humberto M.F.; Manfio, Gilson P.; Maranhao, Andrea Q.; Martinkovics, Christyanne T.; Medeiros, Silvia R.B.; Moreira, Miguel A.M.; Neiva, Marcia; Ramalho-Neto, Cicero E.; Nicolas, Marisa F.; Oliveira, Sergio C.; Paixao, Roger F.C.; Pedrosa, Fabio O.; Pena, Sergio D.J.; Pereira, Maristela; Pereira-Ferrari, Lilian; Piffer, Itamar; Pinto, Luciano S.; Potrich, Deise P.; Salim, Anna C.M.; Santos, Fabricio R.; Schmitt, Renata; Schneider, Maria P.C.; Schrank, Augusto; Schrank, Irene S.; Schuck, Adriana F.; Seuanez, Hector N.; Silva, Denise W.; Silva, Rosane; Silva, Sergio C.; Soares, Celia M.A.; Souza, Kelly R.L.; Souza, Rangel C.; Staats, Charley C.; Steffens, Maria B.R.; Teixeira, Santuza M.R.; Urmenyi, Turan P.; Vainstein, Marilene H.; Zuccherato, Luciana W.; Simpson, Andrew J.G.; Zaha, Arnaldo
Source
Journal of Bacteriology. August 2005, Vol. 187 Issue 15-16, p5568, 10 p.
Subject
Language
English
ISSN
0021-9193
Abstract
This work reports the results of analyses of three complete mycoplasma genomes, a pathogenic (7448) and a nonpathogenic (J) strain of the swine pathogen Mycoplasma hyopneumoniae and a strain of the avian pathogen Mycoplasma synoviae; the genome sizes of the three strains were 920,079 bp, 897,405 bp, and 799,476 bp, respectively. These genomes were compared with other sequenced mycoplasma genomes reported in the literature to examine several aspects of mycoplasma evolution. Strain-specific regions, including integrative and conjugal elements, and genome rearrangements and alterations in adhesin sequences were observed in the M. hyopneumoniae strains, and all of these were potentially related to pathogenicity. Genomic comparisons revealed that reduction in genome size implied loss of redundant metabolic pathways, with maintenance of alternative routes in different species. Horizontal gene transfer was consistently observed between M. synoviae and Mycoplasma gallisepticum. Our analyses indicated a likely transfer event of hemagglutinin-coding DNA sequences from M. gallisepticum to M. synoviae.