부산대학교 도서관

Aim: This study aimed to verify the correlation between murine measurements and retroperitoneal adipose tissue in rats exposed to the high-fat diet. Material and methods: Wistar male adult rats, descendants of mothers who consumed a high-fat diet during pregnancy and lactation and fed the same diet after weaning were used. At 60 days of life, body weight, longitudinal axis and waist circumference (WC) were measured. The Body Mass Index (BMI) and the Lee Index were calculated for a posterior analysis of the correlation with the amount of retroperitoneal adipose tissue dissected on the same day. For analysis of the data, the Pearson correlation test was used, considering statistical significance for p Keywords: high-fat diet, obesity, rats, murinometric index, retroperitoneal adipose tissue. Objetivo: Este estudo teve como objetivo verificar a correlacao entre medidas murinometricas e tecido adiposo retroperitoneal em ratos expostos a dieta hiperlipidica. Material e metodos: Foram utilizados ratos Wistar machos adultos, descendentes de maes que consumiram dieta hiperlipidica durante a gestacao e lactacao e alimentados com a mesma dieta apos o desmame. Aos 60 dias de vida, foram medidos o peso corporal, o eixo longitudinal e a circunferencia da cintura (CC). O Indice de Massa Corporal (IMC) e o Indice de Lee foram calculados para posterior analise da correlacao com a quantidade de tecido adiposo retroperitoneal dissecado no mesmo dia. Para analise dos dados, utilizou-se o teste de correlacao de Pearson, considerando significancia estatistica para p Palavras-chave: dieta hiperlipidica, obesidade, ratos, indice murinometrico, tecido adiposo retroperitoneal.
1. Introduction Obesity is considered a public health problem due to the high prevalence and its comorbidities (Banik and Rahman, 2018; Luz et al., 2017). The accumulation of fat in [...]