학술논문

The selfishly selfless placenta
Document Type
Academic Journal
Source
Journal of Clinical Investigation. February 2020, Vol. 130 Issue 2, p590, 3 p.
Subject
Iron deficiency anemia
Fetal development
Pregnancy
Pregnant women
Setting (Literature)
Commodity markets
Newborn infants
Public health
Women
Anemia
Public health movements
Health care industry
International economic relations
Language
English
ISSN
0021-9738
Abstract
Although iron deficiency continues to pose a problem for pregnant women and fetal development, an incomplete understanding of placental adaptation to limited iron availability has hindered efforts to identify optimal supplementation strategies. In this issue of the JCI, Sangkhae et al. used mouse models and human placentas to explore maternal, placental, and fetal responses to alterations in iron status during pregnancy. The authors identified molecular mechanisms that limit placental ability to upregulate iron transport in the setting of severe iron deficiency and explored a potential marker of placental maladaptation.
Deficiency anemia in pregnant women Iron deficiency during pregnancy continues to present a major public health concern. Even in developed parts of the world, most women of reproductive age require [...]