학술논문
Clinicopathologic analysis and surgical outcome of adrenal lesions--A single centre experience
Original Research Article
Original Research Article
Document Type
Report
Author
Source
Journal of Evolution of Medical and Dental Sciences. June 5, 2017, Vol. 6 Issue 45, p3498, 5 p.
Subject
Language
English
ISSN
2278-4748
Abstract
BACKGROUND Adrenal lesions (Solid and cystic) although rare, can present with wide spectrum of manifestations. Prevalence in the autopsy series varies from 3 to 5%. [1] With widespread use of [...]
BACKGROUND Adrenal lesions are uncommon, often present with wide spectrum of manifestations, ranging from silent, benign incidentaloma to functional and rarely highly malignant neoplasm. We present our institutional experience regarding evaluation, management and outcome of adrenal lesions. MATERIALS AND METHODS A retrospective study was carried out in patients who had undergone adrenalectomy at our institution from 2009 to 2017. RESULTS A total of 41 patients underwent adrenalectomy during this period. Mean patient age was 45.7 years. Slight male (M/F =25/16) and left side (R/L = 17/24) predominance was noted. Silent incidentaloma 21 (52%) was the most common presentation. Similarly, the lesion was biochemically inert in 26 (63.4%) cases. As compared to open adrenalectomy, blood loss (P=0.02), analgesic requirement (P = 0.04) and duration of hospital stay (P=0.017) was significantly lesser in laparoscopic group. Histopathological examination revealed a benign lesion in 38 (93.7%) cases. Mean duration of followup was 18.5 months. There was no evidence of recurrence in benign lesions. CONCLUSION A diligent evaluation is required in all cases in order to characterise these adrenal lesions. Benign lesions, when excised completely, result in excellent long term outcome. Minimally invasive surgery is preferred because of minimal blood loss, shorter hospital stay and better cosmesis as compared to open methods. KEYWORDS Adrenal Lesions, Incidentaloma, Laparoscopic Adrenalectomy.
BACKGROUND Adrenal lesions are uncommon, often present with wide spectrum of manifestations, ranging from silent, benign incidentaloma to functional and rarely highly malignant neoplasm. We present our institutional experience regarding evaluation, management and outcome of adrenal lesions. MATERIALS AND METHODS A retrospective study was carried out in patients who had undergone adrenalectomy at our institution from 2009 to 2017. RESULTS A total of 41 patients underwent adrenalectomy during this period. Mean patient age was 45.7 years. Slight male (M/F =25/16) and left side (R/L = 17/24) predominance was noted. Silent incidentaloma 21 (52%) was the most common presentation. Similarly, the lesion was biochemically inert in 26 (63.4%) cases. As compared to open adrenalectomy, blood loss (P=0.02), analgesic requirement (P = 0.04) and duration of hospital stay (P=0.017) was significantly lesser in laparoscopic group. Histopathological examination revealed a benign lesion in 38 (93.7%) cases. Mean duration of followup was 18.5 months. There was no evidence of recurrence in benign lesions. CONCLUSION A diligent evaluation is required in all cases in order to characterise these adrenal lesions. Benign lesions, when excised completely, result in excellent long term outcome. Minimally invasive surgery is preferred because of minimal blood loss, shorter hospital stay and better cosmesis as compared to open methods. KEYWORDS Adrenal Lesions, Incidentaloma, Laparoscopic Adrenalectomy.