학술논문

INTERACTION OF SILVER NANOPARTICLES WITH VANCOMYCIN: AN UV-VIS STUDY
Document Type
Academic Journal
Source
Studia Universitatis Babes-Bolyai. Chemia. June, 2019, Vol. 64 Issue 2, p335, 9 p.
Subject
Ultraviolet-visible spectroscopy
Nanoparticles
Vancomycin
Silver
Antibacterial agents
Spectroscopy
Novels
Language
English
ISSN
1224-7154
Abstract
Silver nanoparticles (AgNPs) were synthesized by chemical reduction method, using different reducing systems. The interaction of AgNPs and vancomycin hydrochloride (V) was investigated by UV-Vis spectroscopy, and their tendency to form AgNP@V associations or complexes was identified in colloidal solutions. Moreover their affinity to self-assembly and aggregate is also examined. This behavior is important and decisively influences the antimicrobial effect of AgNP@V complexes. Keywords: silver nanoparticles, vancomycin, UV-VIS spectroscopy
INTRODUCTION The current need for novel syntheses and functionalization methods of silver nanoparticles (AgNPs) for gaining an enhanced antimicrobial activity represents a great challenge in the development of new antimicrobials. [...]