부산대학교 도서관

Background: The 6-min walk test (6MWT) allows exercise tolerance to be assessed, and it has a significant prognostic value in COPD. The goal of this study was to analyse the determinants (obtained in routine practice) of a low 6-min walking distance (6MWD) and exercise-induced desaturation (EID) in COPD, including comorbidities. Methods: Patients were recruited from the real-life French COPD cohort "Initiatives BPCO". A low 6MWD was defined as 30 kg/m ), low BMI (BMI Results: Among 440 patients with available 6MWT data, a 6MWD Conclusion: 6MWD and EID exhibit different determinants in COPD with a minor impact of comorbidities limited to hypertension in EID and to obesity, which was unexpectedly associated with less EID. Other variables including age, routine resting lung function and SpO2 were weakly associated with 6MWD and EID. Altogether, these results suggest that 6MWT performance remains difficult to predict with routine clinical/functional parameters. Keywords: 6-min walk test, distance, COPD, obesity, comorbidities, severity
Background COPD is worldwide a leading cause of mortality and morbidity (1,2) associated with progressive airflow limitation. Until recently, COPD severity was mainly defined by the level of post-bronchodilator [FEV.sub.1]. [...]