학술논문

Workplace Drug Testing As A Drug Prevention Strategy for Public Transport Drivers: A Cross-sectional Study/ Toplu Tasma Suruculerinde Madde Kullanimini Onleme Stratejisi Olarak Isyeri Madde Testleri: Kesitsel Bir Calisma
Document Type
Report
Source
The Bulletin of Legal Medicine (Adli Tıp Bulteni). April, 2024, Vol. 29 Issue 1, p29, 6 p.
Subject
Turkey
Language
English
ISSN
1300-865X
Abstract
Objective: Workplace drug testing for public transport drivers is required to apply or renew their driver's certificate as well as a psychological evaluation according to the decision taken by the Adana Municipality Transportation Coordination Center in May 2015. In the context of this study, our objective is to safeguard both the rights of public transportation drivers who have tested positive for illicit substances and the safety of passengers. To this end, we aimed to corroborate the presence of these substances in urine or hair samples through liquid chromatography/ tandem mass spectrometry and to provide a nuanced interpretation of the results. Methods: The sample of the study consisted of 35 drivers who applied to the Forensic Toxicology Laboratory of Cukurova University, Department of Forensic Medicine, for confirmation analysis between January 2019 and December 2022. Opioids, cocaine, marijuana, amphetamines and their derivatives, benzodiazepine, buprenorphine, and synthetic cannabinoids were confirmed by liquid chromatography/tandem mass spectrometry in the urine or hair samples of 35 drivers. Results: All of 35 public transport drivers were male in this study and the mean age was 48.8[+ or -]9.1 years old. The most detected substance in urine by immunoassay test were benzodiazepine, amphetamine and opiate, respectively. However, 91.5% of drivers showed false positive results in confirmatory methods. Benzodiazepine was detected in only 5% by liquid chromatography/tandem mass spectrometry while more than half of the 35 samples were positive for benzodiazepine in screening test. Conclusion: Immunoassay tests are susceptible to generating false positive results due to the cross-reactivity of analytes. Keywords: Workplace, drug testing, urine, hair Amac: Adana Buyuksehir Belediyesi Ulasim Koordinasyon Merkezi'nin Mayis 2015'te aldigi karara gore, toplu tasima araci kullanabilmek icin gerekli olan sofor uygunluk belgesine ilk kez basvuruda ya da yenilemede soforlere psikolojik degerlendirmenin yani sira isyeri madde testi yaptirma zorunlulugu getirilmistir. Calismamizda idrarda immunoassay yontem ile yasa disi madde testi pozitif cikan soforlerin hak kayiplarini engellemek ve/veya yolcu guvenligini korumak icin idrar veya sac orneklerinde bu maddelerin sivi kromatografi/tandem kutle spektrometresi ile dogrulanmasi, her iki yontemden elde edilen sonuclarin karsilastirilmasi ve sonuclarin yorumlanmasi amaclanmistir. Yontem: Calismanin orneklemini Ocak 2019 ile Aralik 2022 donemi boyunca Cukurova Universitesi Adli Tip Anabilim Dali Adli Toksikoloji Laboravutari'na dogrulama analizi icin basvuran 35 surucu olusturmaktadir. Bir dis merkezde idrarda yasa disi madde testi yapilan ve sonucu pozitif cikan 35 surucunun idrar ya da sac orneklerinde opiyat, kokain, esrar, amfetamin ve turevleri, benzodiazepin, buprenorfin, ve sentetik kannabinoidler sivi kromatografi/tandem kutle spektrometrisi ile taranmistir. Bulgular: Bu calismaya katilan 35 toplu tasima surucusunun tamami erkek ve yas ortalamasi 48,8[+ or -]9,1 idi. Idrarda on tarama testinde yaygin olarak benzodiazepin, amfetamin ve opiyat tespit edilmistir. Suruculerin idrar ya da sac orneklerinde sivi kromatografi/tandem kutle spektrometrisi ile yapilan dogrulama analizinde %91,5'inin yanlis pozitif sonuclar verdigi gozlemlenmistir. Otuz bes surucunun yarisindan fazlasinda on tarama testinde benzodiazepin pozitif cikarken, dogrulama yonteminde sadece %5'inde benzodiazepin pozitif tespit edilmistir. Sonuc: Immunoassay testler, analitlerin capraz reaktivitesi nedeniyle yanlis pozitif sonuclar uretmeye duyarlidir. Bu nedenle hem isverenin hem de calisanin haklarini korumak icin pozitif sonuclarin dogrulanmasi gerekmektedir. Ayrica on tarama testlerinde sadece pozitif sonuclarin degil yanlis negatif sonuclarin da gozden kacmamasi icin spesifik ve hassas yontemler kullanilmasina dikkat edilmelidir. Anahtar Kelimeler: Isyeri, madde testi, idrar, sac
GIRIS Bir ulkenin ekonomisinde gider hesaplanirken yuksek isci tazminatlari ve sigorta maliyetlerini goz onunde bulundurmak gerekir. Isyerlerinde calisanin madde kullanimi; verimliligi dusurmesi, devamsizligi artirmasi ve daha fazla isyeri kazalarina neden [...]