학술논문
Cardiopulmonary receptor and arterial baroreceptor reflexes after acute myocardial infarction
Coronary Artery Disease
Coronary Artery Disease
Document Type
Periodical
Author
Source
American Journal of Cardiology. April 1, 1992, Vol. 69 Issue 9, p873, 6 p.
Subject
Language
ISSN
0002-9149
Abstract
The baroreceptor-heart rate reflex in human is impaired 2 days after a myocardial infarction but it improves 10 days after the acute coronary event. This study investigated whether (1) the baroreceptor-heart rate reflex improvement takes the reflex back to normal, and (2) the cardiopulmonary reflex is affected by myocardial infarction. In subjects studied 8 to 11 days after a transmural anterior or inferior myocardial infarction the baroreceptor-heart rate reflex sensitivity (slope of the linear regression between negative neck chamber pressures and lengthenings in RR interval) was similar to that seen in control subjects (-6.2 [+ or -] 0.8 vs -6.0 [+ or -] 0.6 ms/mm Hg, mean [+ or -] SEM) and did not change when reassessed 10 days later. In contrast, the cardiopulmonary reflex sensitivity (changes in forearm vascular resistance induced by changing central venous pressure through non-hypotensive lower body suction and leg raising) was markedly less in subjects studied 8 to 11 days after myocardial infarction than in control subjects; the reduction amounted to 58.1 [+ or -] 8% (p