학술논문
Nitroimidazoles for imaging hypoxic myocardium
Document Type
Academic Journal
Author
Source
Journal of Nuclear Cardiology. Sept-Oct, 1995, Vol. 2 Issue 5, p437, 9 p.
Subject
Language
English
ISSN
1071-3581
Abstract
A series of radiopharmaceuticals that incorporate nitroimidazole moieties have beensynthesized to detect decreased local tissue pO2. In contrast to agents that localize in proportion to perfusion, these agents concentrate in hypoxic tissue. Myocardium with an intracellular pO2