학술논문

Bioinformatic analyses of CALR mutations in myeloproliferative neoplasms support a role in signaling
Document Type
Report
Source
Leukemia. October 1, 2014, Vol. 28 Issue 10, p2106, 4 p.
Subject
Gene mutations -- Research -- Physiological aspects
Computational biology -- Analysis
Myeloproliferative disorders -- Analysis -- Genetic aspects
Cellular signal transduction -- Research -- Physiological aspects
Language
English
ISSN
0887-6924
Abstract
Basic AA (H +K+R): (B + D + E + Z): Basic AA Acidic AA (0.1337 MF)
Most of JAK2 V617F-negative essential thrombocythemia (ET) and primary myelofibrosis (PMF) patients have mutations in CALR, the gene that encodes calreticulin. (1,2) All CALR mutations were indels located in the [...]