부산대학교 도서관

Objective. To assess growth retardation in male adolescent patients who have a diagnosis of anorexia nervosa (AN) and the effect of weight restoration on catch-up growth. Methods. Medical charts of all male adolescent AN patients (n = 12) who were admitted to the Pediatric Psychosomatic Department at the Sheba Medical Center from January 1, 1994, to December 31, 1998, were reviewed. Height and weight measurements were obtained before the onset of AN, at admission, and thereafter routinely during hospitalization and follow-up. Results. Eleven patients exhibited growth retardation during the course of their illness, as evident in a decrease in their height standard deviation score (SDS). The mean height SDS at the time of admission (-0.81 [+ or -] 0.93) was significantly lower than the premorbid SDS (-0.21 [+ or -] 0.91). Weight restoration resulted in accelerated linear growth (up to 2 cm/mo) in all patients. Positive weight gain (weight gain rate >1 kg/y) was associated with a mean height gain of 6.97 [+ or -] 6.48 cm/y, whereas weight loss or failure to gain weight (weight gain rate [less than or equal to] 1 kg/y) was associated with a mean of 2.7 [+ or -] 3.9 cm/y. This between-group difference was highly significant. Complete catch-up growth was not achieved in 9 of 12 patients. There was a trend for the mean adult final height SDS (-0.52 [+ or -] 0.84) to be higher than the admission height SDS but lower than both the premorbid height SDS and the midparental target height SDS (-0.21 [+ or -] 0.79). Conclusions. Linear growth retardation was a prominent feature of AN in our sample of male adolescent patients, preceding, in some cases, the reported detection of the eating disorder. Weight restoration, particularly when target weight is based on the premorbid height percentile, may be associated with significant catch-up growth, but complete catch-up growth may not be achieved. Pediatrics 2003;111:270-276; anorexia nervosa, growth failure, final height, malnutrition, male.
ABBREVIATIONS. AN, anorexia nervosa; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; SDS, standard deviation scores; IBW, ideal body weight. The need for adequate caloric intake, weight gain, [...]