학술논문

A mechanism of palindromic gene amplification in Saccharomyces cerevisiae
Document Type
Academic Journal
Source
Genes & Development. June 1, 2005, Vol. 19 Issue 11, p1390, 10 p.
Subject
DNA -- Research
Gene amplification -- Research
Brewer's yeast -- Genetic aspects
Genetic research
Language
English
ISSN
0890-9369
Abstract
A recombination substrate in Saccharomyces cerevisiae that frequently generates palindromic duplications to repair a site-specific double-stand break in strains deleted for the SAE2 gene is made. Observations show that palindromes are stable in SAE2delta cells, but unstable in wild-type cells.