학술논문

A case of persistent bacteraemia by Ralstonia mannitolilytica and Ralstonia pickettii in an intensive care unit
Document Type
Academic Journal
Source
Infection and Drug Resistance. August, 2019, p2391, 5 p.
Subject
Imipenem -- Health aspects
Thrombosis -- Health aspects
Beta lactamases -- Health aspects
Infection -- Health aspects
Aneurysm -- Health aspects
Genetic research
Genes
Microbiology
Bacteria
Fermentation
Pathogenic microorganisms
Gram-negative bacteria
Language
English
ISSN
1178-6973
Abstract
The Ralstonia spp. genus is a group of non-fermentative, Gram-negative bacteria often resistant to many antibiotics, which are emerging as opportunistic pathogens frequently associated with infections in hospital settings. We present herein a case of combined R. pickettii and R. mannitolilytica persisting and relapsing bacteraemia, possibly caused by a septic arterial thrombosis secondary to the rupture of an internal carotid artery aneurysm. Microbiology studies showed that both Ralstonia isolates produced biofilm and carried class D oxacillinase genes. When confronted with infections caused by members of the Ralstonia genus, identification to the species level is crucial for correct clinical management, as the two species show different antibiotic susceptibility patterns. Keywords: Ralstonia pickettii, Ralstonia mannitolilytica, bacteraemia, endovascular infection
Background Members of the Ralstonia genus are emerging opportunistic pathogens that include R. pickettii, R. mannitolilytica, R. solanacearum, and R. insidiosa. R. pickettii and R. mannitolilytica have been involved in [...]