학술논문
Enhanced ternary 1:2 host-guest complexation of amino-I3-cyclodextrins with 2-anthracenecarboxylic acid
Document Type
Author abstract
Author
Source
Journal of Inclusion Phenomena and Macrocyclic Chemistry. April, 2007, Vol. 57 Issue 1-4, p433, 5 p.
Subject
Language
English
ISSN
0923-0750
Abstract
The complexation behavior of 6-amino-6-deoxy-I3-cyclodextrin (CD), 6.sup.A,6.sup.X-diamino-6.sup.A,6.sup.X-deoxy-I3-CDs and 3.sup.A-amino-3.sup.A-deoxy-altro-I3-CD with 2-anthracenecarboxylic acid (AC) was studied by NMR, UV--vis and circular dichroism spectroscopy. These modified I3-CD derivatives were found to form stable 1:2 host-guest ternary complexes with AC in aqueous solution. Compared with native I3-CD, the primary-face-aminated I3-CDs exhibited remarkably enhanced overall association constants as a result of the additional electrostatic interactions between the oppositely charged host and guest. In contrast, the ternary complex formation of the secondary-face-aminated I3-CD with AC was hindered.