학술논문
Effect of 12-week home-based cognitive training on cognitive function and brain metabolism in patients with amnestic mild cognitive impairment
Document Type
Academic Journal
Author
Source
Clinical Interventions in Aging. June, 2019, p1167, 9 p.
Subject
Language
English
ISSN
1178-1998
Abstract
Purpose: We assessed the effect of home-based cognitive intervention (HCI) on cognitive function along with brain metabolism by 18F-FDG PET in patients with amnestic MCI (aMCI). Patients and methods: Fifty-seven patients with aMCI from three hospitals were randomized (30 HCI, 27 control). For 12 weeks, subjects received HCI. Thirty-two subjects (15 HCI, 17 control) underwent brain 18-F-FDG-PET imaging at baseline and at 12 and 24 weeks. Results: The HCI group showed significant improvement in the scores of the Controlled Oral Word Association Test (COWAT) 12 and at 24 weeks. Significant brain metabolic changes by 18F-FDG PET were not observed. Conclusion: The current study suggests that HCI was effective in improving general cognition along with frontal executive function in patients with aMCI. Keywords: mild cognitive impairment, cognitive training, brain PET
Introduction With an increasingly aging society, the percentage of the population with cognitive decline is rising rapidly. Mild cognitive impairment (MCI) is a heterogenic condition that has a high risk [...]
Introduction With an increasingly aging society, the percentage of the population with cognitive decline is rising rapidly. Mild cognitive impairment (MCI) is a heterogenic condition that has a high risk [...]