학술논문
Development of PTH Eluting Microspheres for the Treatment of Hypoparathyroidism
Document Type
Report
Author abstract
Author abstract
Author
Source
Journal of Surgical Research. Dec, 2007, Vol. 143 Issue 2, p195, 5 p.
Subject
Language
English
ISSN
0022-4804
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jss.2006.04.009 Byline: Peter Fong ([cor]), Amit Goyal ([cor]), Matthew Brennan ([cor]), Jason Park, Lawrence Moss ([cor]), W. Mark Saltzman, Christopher K. Breuer ([cor]) Keywords: parathyroid hormone (PTH); microspheres; drug delivery; negative feedback Abstract: Parathyroid hormone (PTH) replacement has been demonstrated to be superior to conventional treatment with calcium supplementation and vitamin D analogs for the treatment of hypoparathyroidism. In this investigation we evaluated the feasibility of using PTH microsphere encapsulation as a potential delivery system for PTH. Author Affiliation: ([cor]) Department of Surgery, Yale University School of Medicine, New Haven, Connecticut (a ) Department of Biomedical Engineering, Yale University School of Medicine, New Haven, Connecticut Article History: Received 4 August 2005