부산대학교 도서관

Background: Parasitic infections are known causes of morbidity among HIV-infected patients with low CD[4.sup.+] counts who are on antiretroviral therapy (ART), mainly as a result of immuno suppression. This study aimed to assess the extent of intestinal parasitic infection and related risk factors among HIV-infected patients attending ART clinic at Debretabor General Hospital, Northern Ethiopia. Methods: A health facility-based cross-sectional study was conducted on 383 HIV-infected patients attending the ART clinic of Debretabor General Hospital, northern Ethiopia from December 2018 to March 2019. An interview-based structured questionnaire was used to gather sociodemographic and risk-factor data. About 5 g fresh stool and 4 mL venous blood were collected from each patient, then transported and tested in accordance with laboratorystandard operating procedures. Data obtained were entered into SPSS version 22.0 and analyzed. P Results: The overall prevalence of intestinal parasites was 25.3%, with 18% and 23.8% by direct wet-mount and formol ether-concentration technique, respectively. Eight (2.1%) patients were infected by multiple parasites using the concentration technique. Ascaris lumbricoides was the most frequently identified parasite (n=23, 25.3%). Parasitic infection was significantly higher among illiterates (P=0.011), patients with CD4 count Conclusion: Relatively higher prevalence of intestinal parasitic infection was found among HIV/AIDS patients. The distribution of intestinal parasites was greatly affected by illiteracy, reduced CD[4.sup.+] counts, and absence of a toilet. Therefore, HIV/AIDS patients with low CD[4.sup.+] counts should be diagnosed consistently for intestinal parasites with routine stool examinations, and awareness creation should be advocated to be included as an essential component of ART-monitoring strategies for improved patient care. Keywords: antiretroviral therapy, debretabor, HIV/AIDS, intestinal parasites, risk factors
Introduction HIV is a challenging health problem worldwide. Based on a joint report from the World Health Organization (WHO) and United Nations Programme on HIV/AIDS, about 38 million individuals were [...]