학술논문
Ophthalmologic Manifestations as Initial Presentation of Patients with Chronic Myeloid Leukemia: Report of Two Cases
Document Type
Clinical report
Author
Source
Case Reports in Oncology. January 2020, Vol. 13 Issue 1, p7, 5 p.
Subject
Language
English
Abstract
Author(s): Shehab F. Mohamed (corresponding author) [a]; Ahmed Qatami [b]; Abdulqadir Nashwan [a]; Mohammad A. Abdulla [a]; Mohamed A. Yassin [a] Introduction In 2016, the WHO revised the classifications for [...]
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm, classically described as triphasic disease (chronic, accelerated, and blast). Despite the significant efforts made by different groups to optimize treatment and outcome, there are still unmet needs and unanswered questions. Ophthalmologic manifestations are among the therapeutic challenges. The best available therapy for patients presenting with ophthalmologic manifestations is still unclear. Here we present two cases of CML (chronic phase) with ophthalmologic manifestations as initial presentation, trying to shed light on this important type of presentation and proposing recommendations for hematologists in view of the current literature. Keywords: Chronic myeloid leukemia, Ophthalmologic manifestations, Cancer biology, Drug therapy
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm, classically described as triphasic disease (chronic, accelerated, and blast). Despite the significant efforts made by different groups to optimize treatment and outcome, there are still unmet needs and unanswered questions. Ophthalmologic manifestations are among the therapeutic challenges. The best available therapy for patients presenting with ophthalmologic manifestations is still unclear. Here we present two cases of CML (chronic phase) with ophthalmologic manifestations as initial presentation, trying to shed light on this important type of presentation and proposing recommendations for hematologists in view of the current literature. Keywords: Chronic myeloid leukemia, Ophthalmologic manifestations, Cancer biology, Drug therapy