학술논문
A lasting symbiosis: how the Hawaiian bobtail squid finds and keeps its bioluminescent bacterial partner
Document Type
Report
Source
Nature Reviews Microbiology. October 2021, Vol. 19 Issue 10, p666, 14 p.
Subject
Language
English
ISSN
1740-1526
Abstract
Author(s): Spencer V. Nyholm [sup.1] , Margaret J. McFall-Ngai [sup.2] Author Affiliations: (1) Department of Molecular and Cell Biology, University of Connecticut, Storrs, USA (2) Pacific Biosciences Research Center, Kewalo [...]
For more than 30 years, the association between the Hawaiian bobtail squid, Euprymna scolopes, and the bioluminescent bacterium Vibrio fischeri has been studied as a model system for understanding the colonization of animal epithelia by symbiotic bacteria. The squid-vibrio light-organ system provides the exquisite resolution only possible with the study of a binary partnership. The impact of this relationship on the partners' biology has been broadly characterized, including their ecology and evolutionary biology as well as the underlying molecular mechanisms of symbiotic dynamics. Much has been learned about the factors that foster initial light-organ colonization, and more recently about the maturation and long-term maintenance of the association. This Review synthesizes the results of recent research on the light-organ association and also describes the development of new horizons for E. scolopes as a model organism that promises to inform biology and biomedicine about the basic nature of host-microorganism interactions. In this Review Nyholm and McFall-Ngai describe recent advances in understanding the squid-vibrio symbiosis, specifically the strides that have been made in recent years in the study of bobtail squid symbiosis from the host viewpoint.
For more than 30 years, the association between the Hawaiian bobtail squid, Euprymna scolopes, and the bioluminescent bacterium Vibrio fischeri has been studied as a model system for understanding the colonization of animal epithelia by symbiotic bacteria. The squid-vibrio light-organ system provides the exquisite resolution only possible with the study of a binary partnership. The impact of this relationship on the partners' biology has been broadly characterized, including their ecology and evolutionary biology as well as the underlying molecular mechanisms of symbiotic dynamics. Much has been learned about the factors that foster initial light-organ colonization, and more recently about the maturation and long-term maintenance of the association. This Review synthesizes the results of recent research on the light-organ association and also describes the development of new horizons for E. scolopes as a model organism that promises to inform biology and biomedicine about the basic nature of host-microorganism interactions. In this Review Nyholm and McFall-Ngai describe recent advances in understanding the squid-vibrio symbiosis, specifically the strides that have been made in recent years in the study of bobtail squid symbiosis from the host viewpoint.