부산대학교 도서관

Purpose: To study the clinical benefit of low-level light therapy when associated with intense pulsed light for the treatment of meibomian gland dysfunction. Methods: An observational study. Two groups of patients that were treated with IPL were considered: group 1 (31 subjects, 62 eyes), intense pulsed light followed by low-level light therapy and group 2 (31 subjects, 62 eyes) intense pulsed light alone. In both groups, treatments were performed in 3 sessions and subjects were evaluated at baseline and 3 weeks after the last treatment session. Values are shown as mean difference [+ or -] standard deviation. Results: We observed a significant improvement in OSDI-12 score and lipid layer thickness, in both groups (-22.7 [+ or -] 17.5, p Conclusion: Intense pulsed light seems effective and safe for the treatment of meibomian gland dysfunction, improving symptoms and the tear film lipid layer. This study shows no strong evidence of the benefit of low-level light therapy, but it shows weak evidence that it may further improve aqueous tear production. Keywords: dry eye syndromes, meibomian gland dysfunction, phototherapy, intense pulsed light therapy, low-level light therapy
Introduction Meibomian gland dysfunction (MGD) is currently considered a crucial factor in dry eye disease. (1) The prevalence of MGD ranges from 3.5% to 60%, (2) it leads to patient-reported [...]