학술논문
An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarcation
Document Type
Academic Journal
Author
Gong-Quing Shen; Plow, Edward F.; Topol, Eric J.; Quing K Wang; Cassano, June; Henderson, Susan; Hazen, Stanley L.; Marchant, Kandice; Barnard, John; Correcher, Roberto; Elston, Robert; Park, Jeong Euy; Quansheng Xi; Jing Li; Olivieri, Oliviero; Ying Hu; Girelli, Domenico; Seidelmann, Sara B.; Rao, Shaoqi; Chun Fan; Lin Li
Source
American Journal of Human Genetics. Oct, 2007, Vol. 81 Issue 4, p780, 11 p.
Subject
Language
English
ISSN
0002-9297
Abstract
An analysis of on the candidate genes in the locus involving probands with premature coronary artery disease (CAD) or myocardial infarction (MI) from GeneQuest families without stenosis was detectable by coronary angiography. Result provides evidences that genetic variants in LRP8 can contribute to the development of premature and familial CAD and MI.