학술논문
NALP1 in vitiligo-associated multiple autoimmune disease
Document Type
Academic Journal
Author
Source
The New England Journal of Medicine. March 22, 2007, Vol. 356 Issue 12, p1216, 10 p.
Subject
Language
English
ISSN
0028-4793
Abstract
A study performed fine-scale genetic association and deoxyribonucleic acid (DNA) sequence analyses in 114 families with vitiligo and associated autoimmune and autoinflammatory diseases in order to identify the autoimmunity susceptibility gene on chromosome 17p13. Findings suggest DNA sequence variants in the NALP1 region are associated with the risk of several epidemiologically associated diseases, implicating innate immune system in the pathogenesis of these disorders.