부산대학교 도서관

Purpose. Our objective was to describe the relationship between sepsis syndrome mortality and cognitive and physical disability in elderly persons. Methods. A 1-year consecutive cohort study in clinical beds of a university hospital was performed. Variables were severity of sepsis syndrome, organ failure, functional status, age, sex, and positive cultures Outcomes were in-hospital and l-year mortalities. Results. The study included 137 patients (>70 years), both sexes. Data from 116 (84.5%) patients were obtainable at l-year follow-up. Forty-eight (35%) patients presented with sepsis (11/137, 8%) or severe sepsis (37/137, 27%). Inhospital mortality was 15.3% (0% for sepsis and 21.8% if severe) and increased with organ failure (p < .0001). One-year mortality was 54.78% (63/1 16), mostly related to severe sepsis; predictors were severe organ failure (p < .0001), prior functional status (p = .0005), and Mini-Mental State Examination (p = .03). Prior functional status and organ failure were independent predictors. Conclusions. In-hospital and 1-year mortality increased with septic syndrome severity, prior functional status, and organ failure. Key Words: Sepsis--Septic syndrome--Organ failure--Functional capacity.