학술논문
A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development, and aging
Document Type
Academic Journal
Author
Source
Genes & Development. Sept 1, 2004, Vol. 18 Issue 17, p2120, 14 p.
Subject
Language
English
ISSN
0890-9369
Abstract
Coregulator DIN-1 and DAF-12 is shown interacting physically and genetically to instruct organismal fates. It is proposed that the DIN-1S/DAF-12 complex serves as a molecular switch that implements slow life history alternatives in response to diminished hormonal signals.