학술논문

The genome of Chenopodium quinoa
Document Type
Report
Source
Nature. February 16, 2017, Vol. 542 Issue 7641, p307, 6 p.
Subject
DNA sequencing -- Methods
Quinoa -- Genetic aspects
Environmental issues
Science and technology
Zoology and wildlife conservation
Language
English
ISSN
0028-0836
Abstract
Chenopodium quinoa (quinoa) is a highly nutritious grain identified as an important crop to improve world food security. Unfortunately, few resources are available to facilitate its genetic improvement. Here we report the assembly of a high-quality, chromosome-scale reference genome sequence for quinoa, which was produced using single-molecule real-time sequencing in combination with optical, chromosome-contact and genetic maps. We also report the sequencing of two diploids from the ancestral gene pools of quinoa, which enables the identification of sub-genomes in quinoa, and reduced-coverage genome sequences for 22 other samples of the allotetraploid goosefoot complex. The genome sequence facilitated the identification of the transcription factor likely to control the production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a mutation that appears to cause alternative splicing and a premature stop codon in sweet quinoa strains. These genomic resources are an important first step towards the genetic improvement of quinoa.
Author(s): David E. Jarvis [1]; Yung Shwen Ho [1]; Damien J. Lightfoot [1]; Sandra M. Schmckel [1]; Bo Li [1]; Theo J. A. Borm [2]; Hajime Ohyanagi [3]; Katsuhiko Mineta [...]