부산대학교 도서관

Background To evaluate retinal structural and functional changes after silicone oil (SO) removal in eyes with macula-off rhegmatogenous retinal detachment (RRD). Methods Best-corrected visual acuity (BCVA) testing, microperimetry, and optical coherence tomography angiography were performed in 48 eyes with macula-off RRD before and 3 months after SO removal. The values of healthy contralateral eyes were used as control data. Correlations between retinal vessel density (VD), retinal nerve fiber layer thickness (RNFLT), the interval between retinal detachment and surgery, the duration of SO tamponade, the follow-up time after SO removal, and visual function were analyzed. Results Significant increases in 2[degrees] fixation rate (FR), 4[degrees] FR, 2[degrees] mean retinal sensitivity (MRS), 6[degrees] MRS, parafoveal superficial capillary plexus VD and RNFLT were observed after SO removal (all P < 0.05). The increase of 2[degrees] MRS and 6[degrees] MRS were correlated with the duration of SO tamponade and the follow-up time after SO removal respectively (all P < 0.05). The last 2[degrees] MRS and 6[degrees] MRS were correlated with the duration of SO tamponade, the interval between retinal detachment and surgery, and the follow-up time after SO removal (all P < 0.01). The last FR in RRD eyes was close to that of contralateral eyes (P > 0.05). Conclusion Retinal structure and function improved to different degrees after SO removal. Fixation stability and retinal sensitivity increased more than BCVA postoperatively. Retinal sensitivity, which was affected by the interval between retinal detachment and surgery and the duration of SO tamponade, gradually recovered after SO removal. Keywords: Microcirculation, Microperimetry, Optical coherence tomography angiography, Rhegmatogenous retinal detachment, Silicone oil
Author(s): Ran Dou[sup.1], Rui Li[sup.2], Rui-chan Li[sup.2], Yan-ru Yu[sup.2], Jin-xiu Zhou[sup.2], Rui-mei Li[sup.2], Xia-ping Wang[sup.2], Dong-chang Zhang[sup.2], Jian Jiang[sup.1] and Song Chen[sup.3] Background Silicone oil (SO) -related vision loss (SORVL) [...]