부산대학교 도서관

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.bbadis.2005.09.002 Byline: Marian C. Cheung (a), B. Greg Brown (b), Emily K. Marino Larsen (c), Andrew D. Frutkin (b), Kevin D. O'Brien (b), John J. Albers (a) Keywords: Phospholipid transfer protein; Inflammatory marker; Cardiovascular disease Abstract: Plasma phospholipid lipid transfer protein (PLTP) has several known key functions in lipoprotein metabolism. Recent studies suggest that it also may play a role in the inflammatory response. Inflammatory cell activity contributes to the development of atherosclerosis. To seek further evidence for the association of PLTP with inflammation, we studied the relationship between PLTP activity and five inflammatory markers [C-reactive protein (CRP), serum amyloid A (SAA), interleukin 6 (IL-6), white blood cells (WBC), and fibrinogen] in 93 patients with low HDL and cardiovascular disease (CVD). Plasma PLTP activity had the strongest correlation with CRP (r =0.332, P Author Affiliation: (a) Division of Metabolism, Endocrinology, and Nutrition, University of Washington, 401 Queen Anne Avenue North, Seattle, WA 98109-4517, USA (b) Division of Cardiology, Department of Medicine, University of Washington, Seattle, WA 98109-4517, USA (c) Department of Biostatistics, University of Washington, Seattle, WA 98109-4517, USA Article History: Received 25 July 2005; Revised 2 September 2005; Accepted 7 September 2005