학술논문

Early and Late Response and Glucocorticoid-Sparing Effect of Belimumab in Patients with Systemic Lupus Erythematosus with Joint and Skin Manifestations: Results from the Belimumab in Real Life Setting Study—Joint and Skin (BeRLiSS-JS)
Document Type
Academic Journal
Source
Journal of Personalized Medicine. April 2023, Vol. 13 Issue 4
Subject
Care and treatment
Systemic lupus erythematosus -- Care and treatment
Lupus -- Care and treatment
Skin
Glucocorticoids
Skin manifestations -- Care and treatment
Belimumab
Corticosteroids
Cutaneous manifestations of general diseases -- Care and treatment
Language
English
ISSN
2075-4426
Abstract
Author(s): Margherita Zen [1]; Mariele Gatto [1]; Roberto Depascale [1]; Francesca Regola [2]; Micaela Fredi [2]; Laura Andreoli [2]; Franco Franceschini [2]; Maria Letizia Urban [3]; Giacomo Emmi [3]; Fulvia [...]
Aim. To assess the efficacy of belimumab in joint and skin manifestations in a nationwide cohort of patients with SLE. Methods. All patients with skin and joint involvement enrolled in the BeRLiSS cohort were considered. Belimumab (intravenous, 10 mg/kg) effectiveness in joint and skin manifestations was assessed by DAS28 and CLASI, respectively. Attainment and predictors of DAS28 remission (