학술논문

A marathon run increases the susceptibility of LDL to oxidation in vitro and modifies plasma antioxidants
Document Type
Academic Journal
Source
The American Journal of Physiology. June, 1999, Vol. 276 Issue 6, pE1083, 9 p.
Subject
Marathon running -- Physiological aspects
Low density lipoproteins -- Physiological aspects
Antioxidants -- Physiological aspects
Lipids -- Physiological aspects
Biological sciences
Language
ISSN
0002-9513
Abstract
Physical activity increases the production of oxygen free radicals, which may consume antioxidants and oxidize low-density lipoprotein (LDL). To investigate whether this is true during strenuous aerobic exercise, 11 well-trained marathon runners were studied. Results showed that strenuous aerobic exercise increases the susceptibility of LDL to oxidation in vitro for up to four days. Although the increase in the concentration of plasma total peroxyl radical trapping antioxidant of plasma reflects an increase of plasma oxidant capacity, it appears insufficient to prevent the increased susceptibility of LDL to oxidation in vitro.