부산대학교 도서관

To purchase or authenticate to the full-text of this article, please visit this link: http://dx.doi.org/10.1111/j.1471-0528.2008.01694.x Byline: FC Denison (a), J Price (b), C Graham (c), S Wild (b), WA Liston (d) Keywords: Body mass index; length of gestation; spontaneous onset labour Abstract: Objective To investigate the effect of maternal body mass index (BMI) on postdates pregnancy, length of gestation and likelihood of spontaneous onset of labour at term. Design Retrospective cohort study. Setting Swedish Medical Birth Register. Population A total of 186 087 primiparous women (of whom 143 519 had spontaneous onset of labour at term) who gave birth between 1998 and 2002. Methods Mann-Whitney test, one-way analysis of variance, linear regression and single variable logistic regression. Main outcome measures Postdates pregnancy ([greater than or equal to]294 days or 42.sup.+0 weeks), length of gestation and likelihood of spontaneous onset of labour at term. Results About 6.8% of pregnancies delivered postdates. Higher maternal BMI (kg/m.sup.2) during the first trimester was associated with longer gestation (P < 0.001) as was a greater change in BMI between the first and third trimesters (BMI measured on admission prior to delivery) with mean (SD) gestation at delivery of 280.7 (8.6) and 283.2 (8.6) days for increases in BMI of Conclusions Higher maternal BMI in the first trimester and a greater change in BMI during pregnancy were associated with longer gestation and an increased risk of postdates pregnancy. Higher maternal BMI during the first trimester was also associated with decreased likelihood of spontaneous onset of labour at term and increased likelihood of complications. Author Affiliation: (a )Division of Reproductive and Developmental Sciences, Centre for Reproductive Biology, Queen's Medical Research Institute (b )Department of Public Health Sciences, University of Edinburgh, Edinburgh, UK (c )Epidemiology and Statistics Core Unit, Wellcome Trust Clinical Research Facility, Western General Hospital, Edinburgh, UK (d )Department of Obstetrics and Gynaecology, Simpson Centre for Reproductive Health, Royal Infirmary, Edinburgh, UK Article History: Accepted 23 January 2008. Article note: Dr FC Denison, Division of Reproductive and Developmental Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK. Email fiona.denison@ed.ac.uk