학술논문

Unusual intramolecular N[right arrow]O acyl group migration occurring during conjugation of (-)-DHMEQ with cysteine
Document Type
Report
Source
Bioorganic & Medicinal Chemistry Letters. Sept 15, 2009, Vol. 19 Issue 18, p5380, 3 p.
Subject
Universities and colleges
Cystine
Thiols
Cysteine
Language
English
ISSN
0960-894X
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.bmcl.2009.07.123 Byline: Ikuko Kozawa (a), Kuniki Kato (a), Toshiaki Teruya (b), Kiyotake Suenaga (b), Kazuo Umezawa (a) Keywords: (-)-DHMEQ; Cysteine; NF-[kappa]B; Bioconjugate; Rearrangement Abstract: We observed an unusual intramolecular N[right arrow]O acyl group migration in the course or formation of the (-)-DHMEQ and protected cysteine conjugate. Author Affiliation: (a) Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan (b) Department of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan Article History: Received 13 June 2009; Revised 23 July 2009; Accepted 27 July 2009