학술논문

Case of MOG-IgG-associated disease with ankylosing spondylitis: A rare coexistence
Document Type
Academic Journal
Source
Turkish Journal of Physical Medicine and Rehabilitation. December, 2023, Vol. 69 Issue 4, p545, 4 p.
Subject
Medical research
Medicine, Experimental
Nervous system diseases
Thyroid diseases
Myelin proteins
Ankylosing spondylitis
Tumor necrosis factor
Immunoglobulin G
Language
Turkish
ISSN
1302-0234
Abstract
Myelin oligodendrocyte glycoprotein-associated disease (MOGAD) is an inflammatory neurological disease. It progresses with attacks by affecting the optic nerves and spinal cord. Bilateral or recurrent optic neuritis are the most common findings in adult patients. Its association with systemic autoimmune disorders such as Sjögren syndrome, antiphospholipid syndrome, autoimmune thyroiditis, and celiac disease is rare. The first and only case of MOGAD in a patient with ankylosing spondylitis with a history of anti-tumor necrosis factor-alpha (anti-TNF-[alpha]) use was reported. Herein, we present the coexistence of MOGAD in a patient with AS who did not have a history of anti-TNF-[alpha] therapy. Keywords: Ankylosing spondylitis, myelin oligodendrocyte glycoprotein antibody disease, optic neuritis.
Myelin oligodendrocyte glycoprotein-associated disease (MOGAD) is an inflammatory neurological disease. It progresses with attacks by affecting the optic nerves and spinal cord. Autoimmune demyelination and axonal damage are severe in [...]