학술논문
Supratentorial primitive neuroectodermal tumors: a Canadian pediatric brain tumor consortium report
Document Type
Report
Disease/Disorder overview
Author abstract
Disease/Disorder overview
Author abstract
Author
Source
Journal of Neuro-Oncology. Jan, 2008, Vol. 86 Issue 1, p101, 8 p.
Subject
Language
English
ISSN
0167-594X
Abstract
Introduction Supratentorial primitive neuroectodermal tumors (SPNET) are rare tumors accounting for only 2.5% of childhood brain tumors. The purpose of this study was to describe the range of treatment regimens used to treat pediatric SPNET in Canada and to identify prognostic factors for overall survival in this population. Methods This study was a retrospective clinical analysis of SPNET patients treated over the last 10 years in Canada. A questionnaire was developed and distributed to all institutions in Canada who treat pediatric patients. Data were collected for patients 2 years. Overall survival was not affected by metastatic disease at diagnosis, tumor site, or degree of initial resection. Conclusions Survival is poor in SPNET patients but highest in those who received chemotherapy and radiation therapy. Further studies are needed to improve the survival of these patients.