학술논문

Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS
Document Type
Academic Journal
Source
The New England Journal of Medicine. May 31, 2001, Vol. 344 Issue 22, p1668, 8 p.
Subject
AIDS (Disease) -- Development and progression
HLA histocompatibility antigens -- Health aspects
Genetic polymorphisms -- Health aspects
Language
ISSN
0028-4793
Abstract
A difference in the amino acid sequence of HLA-B*35 can affect an HIV patient's progression to AIDS. In some cases, a single amino acid change can affect this protein that is involved in the immune system response to infections.