학술논문
IS IT TIME TO REDEFINE COGNITIVE DYSFUNCTION AFTER CARDIAC SURGERY? THE IMPORTANCE OF METHODOLOGICAL CONSISTENCY
Document Type
Report
Author
Source
Acta Clinica Croatica. March 2021, Vol. 60 Issue 1, p127, 4 p.
Subject
Language
English
ISSN
0353-9466
Abstract
Introduction Postoperative cognitive dysfunction (POCD) following cardiac surgery represents a major concern for anesthesiologists. Aside from association with markedly adverse outcomes during early postoperative period, including increased mortality, the appearance [...]
High incidence and significance of repercussions on patient health and healthcare system make postoperative cognitive dysfunction (POCD) a major problem following cardiac surgery. POCD frequency drops over time since surgery and its occurrence are related to different aspects of cognitive deterioration that markedly impair the patient quality of life.Therefore, a substantial number of papers have focused on this complex postoperative complication, however, with limited achievement in clarifying it. The underlying mechanisms of POCD development and contributing factors are still unclear. A significant issue in POCD research is the lack of uniformity in defining cognitive impairment among investigators, including unique terminology of cognitive changes, a battery of appropriate neuropsychological tests, timing of assessment, and statistical approach. Thus, the aim of this review is to address the difficulties in establishing POCD definition, with inclusion of specific recommendations based on recent publications. Key words: Cardiac surgical procedures; Cardiopulmonary bypass; Cognition disorders; Cognitive dysfunction; Neuropsychological tests; Postoperative complications
High incidence and significance of repercussions on patient health and healthcare system make postoperative cognitive dysfunction (POCD) a major problem following cardiac surgery. POCD frequency drops over time since surgery and its occurrence are related to different aspects of cognitive deterioration that markedly impair the patient quality of life.Therefore, a substantial number of papers have focused on this complex postoperative complication, however, with limited achievement in clarifying it. The underlying mechanisms of POCD development and contributing factors are still unclear. A significant issue in POCD research is the lack of uniformity in defining cognitive impairment among investigators, including unique terminology of cognitive changes, a battery of appropriate neuropsychological tests, timing of assessment, and statistical approach. Thus, the aim of this review is to address the difficulties in establishing POCD definition, with inclusion of specific recommendations based on recent publications. Key words: Cardiac surgical procedures; Cardiopulmonary bypass; Cognition disorders; Cognitive dysfunction; Neuropsychological tests; Postoperative complications