학술논문

Video microscopy of cerebrocortical capillary flow: response to hypotension and intracranial hypertension
Document Type
Academic Journal
Source
American Journal of Physiology (Consolidated). June 1995, Vol. 268 Issue 6, pH2202, 9 p.
Subject
Research
Physiological aspects
Cerebral circulation -- Research
Intracranial hypertension -- Physiological aspects
Hypotension -- Physiological aspects
Language
ISSN
0002-9513
Abstract
The flow velocity of red blood cells in the cerebrocortical capillaries is unaffected by changes in the cerebral perfusion pressure (CPP) during hemorrhagic hypotension and intracranial pressure as long as the CPP does not fall below the lower limit of cerebral autoregulation. Autoregulation is thus maintained when the arterial pressure decreases or intracranial pressure increases. Unperfused capillaries do not open and there is a decrease in the capillaries' diameter or hematocrit. There is a positive correlation between the red blood cells flux and velocity and capillary recruitment is not involved in the autoregulation.