학술논문
METEOROLOGICAL VARIABLES ASSOCIATED WITH SUBARACHNOID HEMORRHAGE: A SINGLE CENTER STUDY/POVEZANOST METEOROLO?KIH VARIJABLA SA SUBARAHNOIDNIM KRVARENJEM: ISKUSTVO JEDNOG CENTRA
Original Scientific Paper/Sa?etak
Original Scientific Paper/Sa?etak
Document Type
Report
Author
Source
Acta Clinica Croatica. December 2022, Vol. 61 Issue 4, p673, 8 p.
Subject
Language
English
ISSN
0353-9466
Abstract
Introduction Spontaneous subarachnoid hemorrhage (SAH) is a major condition with the annual incidence of approximately 91 per 100 000. The vast majority of SAH cases, around 85%, are caused by [...]
Spontaneous subarachnoid hemorrhage (SAH) can occur unexpectedly and independently of the classic risk factors. Several different factors could affect intracranial aneurysm (IA) rupture, such as morphological and hemodynamic factors. The aim of this study was to establish the potential association of meteorological data such as temperature, atmospheric pressure, and humidity, and the onset of clinical symptoms preceding hospital admission of patients with acute SAH due to IA rupture. This retrospective study included 130 consecutive patients admitted for non-traumatic SAH with a determinable onset of SAH symptoms. The effects of meteorological parameters of atmospheric pressure, ambient temperature, and relative air humidity on the day of acute SAH onset and 24 hours prior to the onset of symptoms were recorded and analyzed in each patient. Spearman rank correlation analysis was used to assess the risks of incident SAH on the basis of daily meteorological data. Seasonal incidence of acute SAH showed the peak incidence in winter and a trough in summer, with monthly incidence peak in January and December. The circadian rhythm analysis showed the peak incidence of SAH in the forenoon, followed by the evening. Acute SAH incidence showed moderate positive association with daily atmospheric pressure (p Keywords: Meteorological variables; Subarachnoid hemorrhages; Intracranial aneurysms Spontano subarahnoidno krvarenje (SAH) mo?e nastati neocekivano i neovisno o klasicnim cimbenicima rizika. Nekoliko razlicitih cimbenika mo?e utjecati na rupturu intrakranijske aneurizme (IA), poput morfolo?kih i hemodinamskih cimbenika. Cilj ovoga istra?ivanja bio je utvrditi potencijalnu povezanost meteorolo?kih podataka kao ?to su temperatura, atmosferski tlak i vla?nost te pojave klinickih simptoma prije prijma u bolnicu bolesnika s akutnim SAH-om zbog rupture IA. Ova retrospektivna studija ukljucila je 130 uzastopnih bolesnika primljenih zbog netraumatskog SAH-a s vidljivim pocetkom simptoma SAH-a. Za svakog bolesnika zabilje?eni su i analizirani ucinci meteorolo?kih parametara atmosferskog tlaka, temperature okoline i relativne vla?nosti zraka na dan nastanka akutnog SAH-a i 24 sata prije pojave simptoma. Korelacijska Spearmanova analiza primijenjena je za procjenu rizika od incidentnog SAH-a na temelju dnevnih meteorolo?kih podataka. Sezonska incidencija akutnog SAH-a pokazala je vrhunac incidencije zimi i pad ljeti, s mjesecnim vrhom incidencije u sijecnju i prosincu. Analiza cirkadijanog ritma pokazala je vrhunac incidencije SAH-a u prijepodnevnim satima, a zatim navecer. Ucestalost akutnog SAH-a pokazala je umjereno pozitivnu povezanost s dnevnim atmosferskim tlakom (p Kljucne rijeci: Meteorolo?ke varijable; Subarahnoidno krvarenje; Intrakranijske aneurizme
Spontaneous subarachnoid hemorrhage (SAH) can occur unexpectedly and independently of the classic risk factors. Several different factors could affect intracranial aneurysm (IA) rupture, such as morphological and hemodynamic factors. The aim of this study was to establish the potential association of meteorological data such as temperature, atmospheric pressure, and humidity, and the onset of clinical symptoms preceding hospital admission of patients with acute SAH due to IA rupture. This retrospective study included 130 consecutive patients admitted for non-traumatic SAH with a determinable onset of SAH symptoms. The effects of meteorological parameters of atmospheric pressure, ambient temperature, and relative air humidity on the day of acute SAH onset and 24 hours prior to the onset of symptoms were recorded and analyzed in each patient. Spearman rank correlation analysis was used to assess the risks of incident SAH on the basis of daily meteorological data. Seasonal incidence of acute SAH showed the peak incidence in winter and a trough in summer, with monthly incidence peak in January and December. The circadian rhythm analysis showed the peak incidence of SAH in the forenoon, followed by the evening. Acute SAH incidence showed moderate positive association with daily atmospheric pressure (p Keywords: Meteorological variables; Subarachnoid hemorrhages; Intracranial aneurysms Spontano subarahnoidno krvarenje (SAH) mo?e nastati neocekivano i neovisno o klasicnim cimbenicima rizika. Nekoliko razlicitih cimbenika mo?e utjecati na rupturu intrakranijske aneurizme (IA), poput morfolo?kih i hemodinamskih cimbenika. Cilj ovoga istra?ivanja bio je utvrditi potencijalnu povezanost meteorolo?kih podataka kao ?to su temperatura, atmosferski tlak i vla?nost te pojave klinickih simptoma prije prijma u bolnicu bolesnika s akutnim SAH-om zbog rupture IA. Ova retrospektivna studija ukljucila je 130 uzastopnih bolesnika primljenih zbog netraumatskog SAH-a s vidljivim pocetkom simptoma SAH-a. Za svakog bolesnika zabilje?eni su i analizirani ucinci meteorolo?kih parametara atmosferskog tlaka, temperature okoline i relativne vla?nosti zraka na dan nastanka akutnog SAH-a i 24 sata prije pojave simptoma. Korelacijska Spearmanova analiza primijenjena je za procjenu rizika od incidentnog SAH-a na temelju dnevnih meteorolo?kih podataka. Sezonska incidencija akutnog SAH-a pokazala je vrhunac incidencije zimi i pad ljeti, s mjesecnim vrhom incidencije u sijecnju i prosincu. Analiza cirkadijanog ritma pokazala je vrhunac incidencije SAH-a u prijepodnevnim satima, a zatim navecer. Ucestalost akutnog SAH-a pokazala je umjereno pozitivnu povezanost s dnevnim atmosferskim tlakom (p Kljucne rijeci: Meteorolo?ke varijable; Subarahnoidno krvarenje; Intrakranijske aneurizme