학술논문
Sulfhydryl compounds, captopril, and MPG inhibit complement-mediated myocardial injury
Document Type
Academic Journal
Source
The American Journal of Physiology. Jan, 1994, Vol. 266 Issue 1, pH28, 8 p.
Subject
Language
ISSN
0002-9513
Abstract
Studies of a complement-mediated myocardial injury model reveal that thesulfhydryl compounds captopril and N-(2-mercaptopropionyl)-glycine (MPG) protect the heart against complement-mediated increases in left ventricular end-diastolic pressures and coronary arterial perfusion pressure, whereas enalapril does not confer any profection. The effects of captopril and MPG are concentration-dependent and verifiable with an in vitro red blood cell hemolysis assay.