학술논문

The changing spectrum of hypertension in premature infants
Document Type
Report
Source
Journal of Perinatology. November, 2019, Vol. 39 Issue 11, p1528, 7 p.
Subject
United States
Language
English
ISSN
0743-8346
Abstract
Objective The objective is to document changes in the etiologic spectrum of hypertension in premature infants. Study design We reviewed all cases of systemic hypertension (HTN) in premature infants at two centers over 8 years. Infants were sorted into categorical groups as described in 2012 by Flynn. Analyses included frequency of diagnosis, timecourse of HTN, and diagnostics. Phthalate exposure via intravenous fluid and respiratory equipment was compared among groups and centers. Results One hundred and twenty-nine infants having 130 episodes of HTN met the inclusion criteria. Sixty-five percent of cases were classified as pulmonary and 16% as miscellaneous. Plasma renin activity (PRA) was undetectable or Conclusions High PRA HTN has been replaced by low PRA in most cases, and may be due to phthalate exposure.
Author(s): K. Farnbach [sup.1] , S. Iragorri [sup.1] , A. Al-Uzri [sup.1] , D. Rozansky [sup.1] , R. Forbush [sup.2] , R. Jenkins [sup.1] Author Affiliations: (1) Oregon Health & [...]