학술논문
Factors Associated with Poor Lymph Node Dissection of Colon Neoplasm/Kolon Kanseri Cerrahisinde Yetersiz Lenf Nodu Çikarilmasi ile Iliskili Risk Faktörleri
RESEARCH ARTICLE
RESEARCH ARTICLE
Document Type
Report
Author
Source
Turkish Journal of Colorectal Disease. December 2021, Vol. 31 Issue 4, p322, 8 p.
Subject
Language
English
ISSN
2536-4898
Abstract
Introduction Colon neoplasms are the most common malignant tumor of the gastrointestinal system worldwide and the leading cause of cancer-related morbidity and mortality in Western countries. Approximately 70-80% of colon [...]
Aim: Dissection of [greater than or equal to]12 lymph nodes is recommended for curative surgery of colon neoplasms. The aim was to determine the clinicopathological factors associated with poor lymph node dissection. Method: Patient hospital records in those undergoing surgery due to stage 1-3 colon neoplasm, between January 2009 and December 2017, were retrospectively evaluated. Univariate and multivariate analyses were performed to evaluate the clinical and pathological risk factors associated with poor lymph node dissection. Results: The patient population during the study period numbered 388. Of these, Conclusion: Adequate lymph node dissection for colon neoplasm patients has prognostic significance. Male patients, advanced pT stage neoplasm, and left colon tumors had an increased risk of poor lymph node dissection. Therefore, lymph node dissection should be undertaken particularly meticulously in these patients. Keywords: Colon cancer, colectomy, poor lynph node dissection Amaç: Kolon kanserinin küratif cerrahisinde [greater than or equal to]12 lenf nodunun diseke edilmesi önerilmektedir. Bu çalismada yetersiz lenf nodu diseksiyonuna etki eden klinikopatolojik faktörleri belirlemeyi amaçladik. Yöntem: Ocak 2009-Aralik 2017 tarihleri arasinda evre 1-3 kolon kanseri tanisiyla opere ettigimiz hastalar retrospektif olarak incelenmistir. Yetersiz lenf nodu diseksiyonu için risk faktörü olan klinik ve patolojik veriler tek degiskenli ve çok degiskenli analizlerle degerlendirilmistir. Bulgular: Çalismaya 388 evre 1-3 kolon kanseri hasta dahil edilmistir. Hastalarin %21,9'da Sonuç: Hastalarin büyük kisminda yeterli lenf nodu diseksiyonun saglandigi çalismamizda büyük, pT evresi ileri, sol kolon yerlesimli tümöre sahip erkek hastalarin yetersiz lenf nodu diseksiyonu açisindan artmis riske sahiptir. Anahtar Kelimeler: Kolon kanseri, kolektomi, yetersiz lenf nodu disseksiyonu
Aim: Dissection of [greater than or equal to]12 lymph nodes is recommended for curative surgery of colon neoplasms. The aim was to determine the clinicopathological factors associated with poor lymph node dissection. Method: Patient hospital records in those undergoing surgery due to stage 1-3 colon neoplasm, between January 2009 and December 2017, were retrospectively evaluated. Univariate and multivariate analyses were performed to evaluate the clinical and pathological risk factors associated with poor lymph node dissection. Results: The patient population during the study period numbered 388. Of these, Conclusion: Adequate lymph node dissection for colon neoplasm patients has prognostic significance. Male patients, advanced pT stage neoplasm, and left colon tumors had an increased risk of poor lymph node dissection. Therefore, lymph node dissection should be undertaken particularly meticulously in these patients. Keywords: Colon cancer, colectomy, poor lynph node dissection Amaç: Kolon kanserinin küratif cerrahisinde [greater than or equal to]12 lenf nodunun diseke edilmesi önerilmektedir. Bu çalismada yetersiz lenf nodu diseksiyonuna etki eden klinikopatolojik faktörleri belirlemeyi amaçladik. Yöntem: Ocak 2009-Aralik 2017 tarihleri arasinda evre 1-3 kolon kanseri tanisiyla opere ettigimiz hastalar retrospektif olarak incelenmistir. Yetersiz lenf nodu diseksiyonu için risk faktörü olan klinik ve patolojik veriler tek degiskenli ve çok degiskenli analizlerle degerlendirilmistir. Bulgular: Çalismaya 388 evre 1-3 kolon kanseri hasta dahil edilmistir. Hastalarin %21,9'da Sonuç: Hastalarin büyük kisminda yeterli lenf nodu diseksiyonun saglandigi çalismamizda büyük, pT evresi ileri, sol kolon yerlesimli tümöre sahip erkek hastalarin yetersiz lenf nodu diseksiyonu açisindan artmis riske sahiptir. Anahtar Kelimeler: Kolon kanseri, kolektomi, yetersiz lenf nodu disseksiyonu