부산대학교 도서관

Objective Study the effects of acute and chronic restraint stress on the whole blood concentrations of iron (Fe), zinc (Zn), calcium (Ca), and magnesium (Mg) in mice. Materials and methods Single or repeat restraints were applied to mice to induce acute or chronic stress. The levels of elements in whole blood were determined by flame atomic absorption spectrometry. Results The levels of Fe, Zn, Ca, and Mg in blood in the acute-stress group were 351, 5.05, 60, and 44 ug/ml, respectively, and those in the corresponding control group were 391, 5.90, 59, and 45 ug/ml, respectively. The levels of blood Fe, Zn, Ca, and Mg in the chronic-tress group were 291, 3.62, 59, and 40 ug/ml, respectively, and those in the corresponding control group were 393, 4.82, 48, and 43 ug/ml, respectively. The levels of Fe and Zn in the blood of both the acute-stress and the chronic-stress groups were significantly lower (P Conclusion Acute and chronic restraint stress can cause changes in blood levels of Fe and Zn in mice.