학술논문
Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanisms
Document Type
Academic Journal
Author
Source
Journal of Acquired Immune Deficiency Syndromes (1999). June 1, 2004, Vol. 36 Issue 2, p659, 12 p.
Subject
Language
English
ISSN
1525-4135
Abstract
A child shares major histocompatibility complex (MHC) genes with its mother due to which the transmission of HIV-1 from mother to child is different from other types of HIV-1 transmission. The relevance of these immune mechanisms to HIV-1 transmission is assessed by determining the HLA-B alleles of mother and child.