학술논문

Feasibility of Electronic Medication Monitoring Among Adolescents and Emerging Adults with Sickle Cell Disease
Document Type
Report
Source
Patient Preference and Adherence. December 31, 2023, Vol. 17, p3167, 5 p.
Subject
United States
Language
English
ISSN
1177-889X
Abstract
Purpose: To examine the feasibility of using MEMS[R] bottles to assess adherence among adolescents and emerging adults with sickle cell disease. Patients and Methods: Eighteen non-Hispanic Black participants with HbSS (M = 17.8 years; 61% male) were given a MEMS[R] bottle to store hydroxyurea (n = 14) or deferasirox (n = 4). Results: One hundred percent initiated MEMS[R] use and 61% sustained use through the 18-week study; at follow-up, only 11% returned their bottle on time. Barriers to MEMS[R] use included medication changes and transition to adult care; facilitators included tip sheets and reminders. Conclusion: While MEMS[R] is acceptable to this population, ensuring sustained use and timely provision of bottles will require additional supports. Keywords: adherence, MEMS, medicine, sickle cell anemia
Introduction Due to advancements in uncovering the mechanisms underlying sickle cell disease (SCD), the landscape of SCD treatment is rapidly evolving. (1) Three new medications have been approved for this [...]