학술논문
Vasopressin-elicited water and urea permeabilities are altered in IMCD in hypercalcemic rats
inner medullary connecting duct
inner medullary connecting duct
Document Type
Academic Journal
Author
Source
American Journal of Physiology (Consolidated). May 1998, Vol. 274 Issue 5, pF978, 8 p.
Subject
Language
ISSN
0002-9513
Abstract
The process by which hypercalcemia reduces renal concentrating ability was investigated by measuring the changes in basal and arginine vasopressin (AVP)-induced osmotic water (Pf) and urea (Purea) permeabilities in isolated perfused inner medullary collecting ducts (IMCDs). Results showed that selective changes in IMCD transport occur in hypercalcemia, allowing the body to excrete excess calcium without forming calcium-containing kidney stones.