학술논문

Increase in congenital hypothyroidism in New York State and in the United States
Document Type
Author abstract
Source
Molecular Genetics and Metabolism. July, 2007, Vol. 91 Issue 3, p268, 10 p.
Subject
Hypothyroidism
Genetic disorders
Language
English
ISSN
1096-7192
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ymgme.2007.03.012 Byline: Katharine B. Harris, Kenneth A. Pass Keywords: Congenital hypothyroidism; Newborn screening Abstract: Mandated screening of newborns for congenital hypothyroidism (CH) in NYS was initiated in l978. Currently, every newborn screening program in the U.S. includes CH in its panel. Between 1978 and 2005, 7.4 million newborns were screened for CH in NYS. In NYS, between 1978 and 2005, the incidence of CH has increased by 138%. Nationwide (excluding NYS data), with nearly 58 million infants screened between 1987 and 2002, the incidence has increased 73% between 1987 and 2002. These data and possible reasons for the increases are discussed, though no definitive causes are identified. Author Affiliation: New York State Department of Health, Wadsworth Center, Laboratory of Molecular Screening Technologies, Empire State Plaza, Albany, NY 12201, USA Article History: Received 28 February 2007; Revised 21 March 2007; Accepted 22 March 2007