학술논문
Clinical Course of COVID-19 in a Thalassemia Major Patient who Underwent Haematopoietic Stem Cell Transplantation/Hematopoetik Kok Hucre Nakli Yapilmis Bir Talasemi Major Hastasmda COVID-19'un Klinik Seyri
Case Report
Case Report
Document Type
Clinical report
Source
Bezmialem Science. February 2021, Vol. 9 Issue S1, p91, 3 p.
Subject
Language
English
Abstract
Introduction Novel Coronavirus infection that occured in Wuhan, China in December 2019, has spread rapidly among people and caused pandemic. After isolation and identification of virus, the causative agent was [...]
We herein reported the course of Coronavirus diasease-19 (COVID-19) in a 21-year-old patient with thalassemia majo rdisease. The patient who underwent haematopoietic stem cell transplantation in 2013 and developed alloimmunization, presented with high fever and weakness. His parents have been recently diagnosed with COVID-19. COVID-19 diagnosis was confirmed by real time-polymerase chain reaction (RT-PCR) method in the nasopharyngeal swab sample of the patient while his thorax computed tomography was not found in favor of pneumonia. The patient was treated with hydroxychloroquine 2x200mg and Favipravir 3x600mg. The temperature fell with in three days. The clinical condition of the patient improved rapidly. On the 20th day, he did not have any symptom with a recovery of anemia and lymphopenia, but the RT-PCR result was stil positive. In this case report, we wanted to point out that the course of the COVID-19 is unexpectedly mild in such a patient with thalassemia major. Keywords: COVID-19, thalassemia major, beta-thalassemia Talasemi major hastaligi olan 21 yasindaki bir hastada Koronavirüs hastaligi-19'un (COVID-19) klinik seyri sunulmustur. 2013yihnda hematopoetik kök hücre nakli yapilmis ve alloimmunizasyon gelismis hasta, yüksek ates ve halsizlik sikayeti ile basvurdu. Yakin zamanda anne ve babasi COVID-19 tanisi almisti. Toraks tomografisinde pnömoni lehine bulgu saptanmayan hastanin COVID-19 tanisi nazofarengeal sürüntü örneginde gerçek zamanli polimeraz zincir reaksiyonu (RT-PCR) yöntemiyle dogrulandi. Hastaya hidroksiklorokin 2x200 mg ve favipravir 3x600 mg tedavisi baslandi. Atesi üç gün sonra düstü. Hastanin klinik durumu hizla iyilesti. Anemi ve lenfopenisi düzelen hastanin, tedavinin 20. gününde herhangi bir semptomu yoktu. Ancak RT-PCR sonucu hala pozitif idi. Bu olgu sunumuyla talasemi majörü olan bir hastada, COVID-19'un beklenmedik biçimde hafif seyrettigine dikkati çekmek istedik. Anahtar Sözcükler: COVID-19, talasemi majör, beta talasemi
We herein reported the course of Coronavirus diasease-19 (COVID-19) in a 21-year-old patient with thalassemia majo rdisease. The patient who underwent haematopoietic stem cell transplantation in 2013 and developed alloimmunization, presented with high fever and weakness. His parents have been recently diagnosed with COVID-19. COVID-19 diagnosis was confirmed by real time-polymerase chain reaction (RT-PCR) method in the nasopharyngeal swab sample of the patient while his thorax computed tomography was not found in favor of pneumonia. The patient was treated with hydroxychloroquine 2x200mg and Favipravir 3x600mg. The temperature fell with in three days. The clinical condition of the patient improved rapidly. On the 20th day, he did not have any symptom with a recovery of anemia and lymphopenia, but the RT-PCR result was stil positive. In this case report, we wanted to point out that the course of the COVID-19 is unexpectedly mild in such a patient with thalassemia major. Keywords: COVID-19, thalassemia major, beta-thalassemia Talasemi major hastaligi olan 21 yasindaki bir hastada Koronavirüs hastaligi-19'un (COVID-19) klinik seyri sunulmustur. 2013yihnda hematopoetik kök hücre nakli yapilmis ve alloimmunizasyon gelismis hasta, yüksek ates ve halsizlik sikayeti ile basvurdu. Yakin zamanda anne ve babasi COVID-19 tanisi almisti. Toraks tomografisinde pnömoni lehine bulgu saptanmayan hastanin COVID-19 tanisi nazofarengeal sürüntü örneginde gerçek zamanli polimeraz zincir reaksiyonu (RT-PCR) yöntemiyle dogrulandi. Hastaya hidroksiklorokin 2x200 mg ve favipravir 3x600 mg tedavisi baslandi. Atesi üç gün sonra düstü. Hastanin klinik durumu hizla iyilesti. Anemi ve lenfopenisi düzelen hastanin, tedavinin 20. gününde herhangi bir semptomu yoktu. Ancak RT-PCR sonucu hala pozitif idi. Bu olgu sunumuyla talasemi majörü olan bir hastada, COVID-19'un beklenmedik biçimde hafif seyrettigine dikkati çekmek istedik. Anahtar Sözcükler: COVID-19, talasemi majör, beta talasemi