학술논문
Pressure-overload hypertrophy is unabated in mice devoid of AT(sub 1A) receptors
Document Type
Academic Journal
Author
Source
The American Journal of Physiology. March, 1998, Vol. 274 Issue 3, pH868, 6 p.
Subject
Language
ISSN
0002-9513
Abstract
Cardiac research indicates that mice with no AT (sub 1A) receptors exhibit the same degree of cardiac hypertrophy as wild type mice. This indicates that the renin-angiotensin system (RAS) may not be involved in cardiac hypertrophy physiology. Experiments using the left ventricular hypertrophic response to pressure overload are described. The role of RAS is discussed.