부산대학교 도서관

Disease in infants infected with HIV at birth may be associated with the severity of disease in the mother at the time of delivery. Among 162 HIV-infected infants, the risk of opportunistic infections was about 13% at 18 months and 15% at 36 months. The risk of brain disease was about 10% at 18 months and 11% at 36 months. The risk of either complication at 18 months was 50% among infants born to mothers with advanced disease at delivery and 14% among those born to mothers with less severe disease. Of the infants whose mothers had advanced disease, 44% died before 18 months, compared to 9% of infants whose mothers had less advanced disease. The risk of illnesses and the risk of death was higher among infants whose mothers had HIV-1 antigens, or substances that initiate immune responses to HIV. Thirty-one percent of infants whose mothers had HIV-1 antigens also had detectable antigens, compared to 7% of infants whose mothers did not have antigens.