학술논문

Coagulation disorders during treatment with cefazolin and rifampicin: rare but dangerous
Document Type
Periodical
Source
Journal of Bone and Joint Infection (JBJI). April 1, 2021, Vol. 6 Issue 5, p131
Subject
Rifampin
Language
English
ISSN
2206-3552
Abstract
We describe a 79-year-old man with spondylodiscitis and unknown pathogen, treated with cefazolin and rifampicin. He developed a massive digestive hemorrhage. Prothrombin time was prolonged with severe vitamin-K-dependent clotting-factor deficiency. Severe bleeding can occur during cefazolin and rifampicin use. This deficiency should be assessed before prescribing cefazolin-rifampicin and prothrombin time monitored.
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