학술논문
Effect of female sex hormones on mitochondria: possible role in acute fatty liver of pregnancy
Document Type
Academic Journal
Author
Source
The American Journal of Physiology. Jan, 1995, Vol. 268 Issue 1, pG107, 9 p.
Subject
Language
ISSN
0002-9513
Abstract
Acute fatty liver of pregnancy occurs in females due to the detrimental influences of sex hormones on liver mitochondria. The sex hormones produce a 54 to 77% increase in state 4 respiration and around 34% decrease in fatty acid oxidation, mitochondrial protein recovery and mitochondrial uptake. Several ultrastructural lesions occur in the mitochondria due to these sex hormones.